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- Therefore, an interaction of endogenous elements of the patient’s risk profile in addition to the testosterone dosing could additionally be issues of whether antagonistic occasions occur.
Moreover, a part of endothelial dysfunction has been proposed, which can contribute to abnormal vessel reactivity. However, testosterone in physiologic doses may even be beneficial in patients with angina , have higher ischemic thresholds and improved high quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and increases coronary blood circulate in men with established coronary artery disease . Therefore, an interplay of endogenous components of the patient’s threat profile as properly as the testosterone dosing may be problems with whether antagonistic occasions occur.
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We report a case of an acute ST-segment elevation myocardial infarction in a affected person with traditional cardiac threat components utilizing supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this patient also had polycythemia, probably secondary to high-dose testosterone. The patient underwent successful percutaneous intervention of the best coronary artery. Physicians and sufferers ought to be conscious of the clinical consequences of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).