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Moreover, a component of endothelial dysfunction has been proposed, which can contribute to abnormal vessel reactivity. However, testosterone in physiologic doses might even be helpful in sufferers with angina , have larger ischemic thresholds and improved high quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and will increase coronary blood circulate in men with established coronary artery disease . Therefore, an interplay of endogenous elements of the patient’s risk profile as nicely as the testosterone dosing could also be problems with whether antagonistic occasions happen.

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